Provider: Moravian Museum, Brno, Czech Republic TY - JOUR JO - Anthropologie (Brno) TI - Skeletal and Molecular Evidence for Tuberculosis in a Forensic Case AU - Ubelaker DH AU - Jones EB AU - Donoghue HD AU - Spigelman M Y1 - 2000 VL - 38 IS - 2 PB - Moravian Museum, Brno, Czech Republic SN - 0323-1119 SP - 193 EP - 200 KW - Tuberculosis KW - PCR KW - Molecular KW - Skeletal KW - Forensic N2 - N2 - Analysis of a human skeleton submitted as a forensic case from the American Southwest detected skeletal lesions suggestive of tuberculosis. Molecular analysis, using the polymerase chain reaction, of samples removed from these lesions confirmed the presence of DNA specific for Mycobacterium tuberculosis. Radiocarbon analysis suggests the skeleton is recent but likely dates prior to 1956 AD. This represents the first use of molecular techniques to identify a disease organism in a human skeletonized forensic case and illustrates the potential of this approach for more general forensic analysis. The many sites of bone involvement display the diversity of lesions present within an individual with documented tuberculosis. ER -