Provider: Moravian Museum, Brno, Czech Republic TY - JOUR JO - Anthropologie (Brno) TI - Contributions to the Pathology of Dermatoglyphics in Some Major Brain Affections AU - Ţarcă A Y1 - 2007 VL - 45 IS - 2-3 PB - Moravian Museum, Brno, Czech Republic SN - 0323-1119 SP - 275 EP - 282 KW - Dermatoglyphics KW - Distortions or anomalies KW - Brain affections KW - Epilepsy KW - Autism and infantile encephalopathies KW - Pathology KW - Moldova (Romania) N2 - N2 - The paper synthesizes the existing data on the pathology of dermatoglyphics in three severe brain affections (epilepsy, autism and sekelary IEP-ies), followed upon a total number of 439 subjects (of which 102 are affected by epilepsy, 137 - by infantile autism and 200 - by sekelary IEP-ies) with ages between 2 and 18 years, all coming from the region of Moldova. An important observation to be made is that the ample symptomatic polymorphism of the three congenital maladies, part of them hereditary, should be correlated with the presence - in the digital and palmar dermatoglyphic picture - of some significant distortions or anomalies bearing deep clinical implications, responsible for their deep pathological charge. In each of the three grave brain affections here considered, there appear the same anomalies - the frequency of which, at the level of the whole group, is not very different from one group of affected people to another, being nevertheless sensibly different from that recorded in the apparently normal population from which the patients come, a situation suggesting that the determining factors of the three maladies had manifested themselves in an early stage of prenatal life (more precisely, in the first 3-5 months of intrauterine life), when the epidermal papillary ridges are also finalized, although the debut as such of each of the three affections occurred during post-natal life, under the action of a large range of secondary factors. For many of the palmar anomalies (AR, Cx, Co, t0 and much reduced a-b distance), the highest weight is given by the group of patients with sekelary IEP, while, for LU, tt't'', T11+T12 and the transverse palmar sulcus - by the group of autists and, finally, for the dense network of the ridges from Th/I - by epileptics, a succession actually correlated with the complexity of the clinical picture for the malady by which the subjects of the three groups are affected. More than that, one may also observe that the 10 palmar anomalies here evidenced have, in all cases, the same line of sexual dimorphism, of bilateral differences and of their arrangement in the carriers' palm, all these aspects suggesting a quite unitary dermatoglyphic behaviour of theirs. The results obtained by the author - the first ones recorded, on a national level, for each of the three affections - might be further used as reference data for their precocious tracing, at populational level, at least in the region of Moldova from where the patients come, while the distortions as such might be viewed as "markers" in the diagnosis of the persons potentially exposed to such maladies. ER -